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Stem Cells Showing Great Promise in Remyelinization - executive Order O.K.s Further Research

A Guest Article by Daryl Clayton Kennedy

There two important pieces of information one must grasp in order to understand how stem cells may unlock breakthrough in treating MS.

 The first is understanding how multiple sclerosis works. The second is understanding research must reach human trials. A compromise has to be bridged between pro life morality and recognizing the imperativeness of providing scientist the tools they need to accumulate precious knowledge.

 In all people, animals even plants there's an ornate ability to heal ourselves of bacterial infection.

 These intrusive microscopic "bugs" (bacteria) are usually defeated in an internal war which we rarely have the privilege of viewing. The troops in these wars are tiny little soldiers known as "T" Cells or Lymphocytes (a unique family of white blood cells).

These warriors are normally welcomed protectors within our body although in the case of individuals suffering from MS, it's theorized these very cells my also be our enemy.

Blood Brain Barrier Penetrated - Myelin Sheath Attacked -  No Hope of Finding Cure Without Myelin Repair

The integrity of the blood brain barrier is in most individuals impermeable to our immune cells.

In the case of MSers, the barrier is some how weakened...(possibly due to infection or other undiscovered external anomalies) and immune cells are able to pass through the membrane only to become trapped once inside.

When these cells enter white matter they simply are unable to differentiate between good and foreign cells. As an instinctive response they begin to attack the myelin sheath surrounding your nerve axons.

This myelin is crucial in the proper conduction of electrical messages firing through your brain.

When these impulses are disrupted as in the case of MSers... the symptoms may, will, and do plague you for life!

Symptoms include:

When these impulses are disrupted as in the case of MSers... the symptoms may, will, and do plague you for life! Symptoms include:

  • Fatigue,
  • Cognitive confusion,
  • Ambulatory difficulty,
  • Uncontrollable muscle Spasms, AND
  • Other neurological symptoms related to nerve conduction.

Until today there has been little hope of curing multiple sclerosis (MS) . One could only rely on palliative solutions to ease symptoms and  transition into this new lifestyle.

Mobility scooters and power chairs have been used to aid with movement due to the diseases devastating ambulatory effects.

Some additional alternative treatments have been 

  • Low Saturated Fat diets, such as the Swank Diet,
  • Yoga,
  • Tai Chi,
  • Cannabis, AND
  • Hyperbaric Chambers. 

The problem with these treatments as stated earlier, is they simply aim to ease our transition into this lifestyle. Their scope does not include the potential resolution of the problem through remyelinization - actual repair of the damaged nerves. 

(Remyelinization is the process in which the sheath surrounding the nerve axon is some how repaired to allow normal signal transfer between nerves.)

Laboratory Mice Prove Stem Cells Capable of Restoring Life into Damaged Myelin

In 2004 scientists at the (RSNA) Radiological Society of North America where able to harvest a primitive form of MS known as experimental autoimmune encephalomyelitis or (EAe) for short.

(EAe) is a working animal model of multiple sclerosis. It possesses characteristics remarkably similar to lesions and symptoms related to the human version of MS.

Mice were injected first with the disease then monitored via use of MRI equipment. Then once found to poses this debilitating disease the mice where injected with (non-human) neural stem cells which according to the RSMA not only showed promise, these stem cells actually where able to restore "some" function in nerve cells, therefore greatly decreasing the symptoms.

As people and mice are without question far apart in anatomy and brain function, there needs to be additional studies in assessing the symptoms and side effects of this non evasive procedure before human trials can safely be attempted.

Ban Lifted on Federal Funding of embryonic Stem Cell Research - Paves Way For Human Trials!

In 2001 the topic of embryonic stem cell research was a touchy subject to say the least.

A ban was placed on research due to the argument that it was a direct infraction on human life. In 2007 that ban was amended and a law put in place that justified human stem cell research in embryos that where smaller than the head of a needle.

These embryos must also be donated by in-vitro fertilization clinics and the cells must be created for the purpose of fertility treatment only. Then, once a woman is successfully fertilized, the “extra” cells could be donated for research. This Bill is now know as the Stem Cell Research enhancement Act of 2007.

March 9, 2009 marked a day of joy for millions of Americans as the newly appointed administration gave a go-ahead for even further research, in hopes that our countries scientists will attack all avenues of this decease and find a cure!

Interesting enough some of the most recent success comes from the United Kingdom where Dr. Doug Brown of the MS Society has been quoted in saying...

"Stem cells are showing more and more potential in the treatment of MS... and the challenge we now face is - proving...their effectiveness in trials involving large numbers of people".
Dr. Doug Brown - MS Society

In addressing this issue, some 21 MSers with (RRMS) Relapsing Remitting MS where given their own stem cells transplanted from their marrow and all participants where reported to have not digressed over a three year period!

Though this may not be a miracle breakthrough, it's a far leap from our progress 10 years ago.

This is great news as it plants a spark of hope in the lives of some 2.3 million suspected MSers around the globe.

About the Guest Author: Daryl Clayton Kennedy is the editor of disabledmobilityscooter.com which discusses disabled mobility scooters and is a regular contributor to mobility and health related blogs throughout the net. Daryl's 3 wheel scooter recommendations and mobility scooter reviews allow you insight on choosing the best mobility scooter for you or your loved one.


Multiple Sclerosis Pages On My Site

Multiple Sclerosis and MeMultiple Sclerosis and My Life: Information about how Multiple Sclerosis has affected me and why I decided to create these pages.  ««»»

Frequently Asked Questions (FAQ)Frequently Asked Questions (FAQ)  ««»»

Multiple Sclerosis LinksMultiple Sclerosis Links and Resources: A boatload of links. Wazillions of links. And a few more. But . . . Even though there are many links here, these are not all the links. Be sure to check the other sections for the specialty links.  ««»»

Local and Non-US OrganizationsLocal and Non-US Organizations: Includes state by state listings of local organizations, including the chapters of the National Multiple Sclerosis Society.  ««»»

Chat, Forums and eMail Discussion Groups  ««»»

Commercial Sites and Commercial JournalsCommercial Sites and Commercial Journals  ««»»

General Medical Sites and Other ResourcesGeneral Medical Sites and Other Resources: Not specifically related to Multiple Sclerosis, but offering general medical information. Many feature search engines to locate Multiple Sclerosis information or Multiple Sclerosis sections within their site.  ««»»

Personal StoriesPersonal Stories: Personal websites featuring the webmaster's personal experience with Multiple Sclerosis. Most also include some links to other Multiple Sclerosis resources.  ««»»

Who Are the People With Multiple Sclerosis?Books: Books about Multiple Sclerosis (like you really needed that description).  ««»»

Who Are the People With Multiple Sclerosis?Who Are the People With Multiple Sclerosis?: A moving essay by Virginia Sanchez (used with permission).  ««»»

Multiple Sclerosis and ChildrenMultiple Sclerosis and Children: Special information about MS in children and why I hope to honor them with my site. ««»»


Who Are the People With Multiple Sclerosis?Guest Article: Social Security and Multiple Sclerosis (MS) - Applying for Social Security Disability with Multiple Sclerosis: A guest article by John Dowling, the Senior editor of Social Security Disability Help.  ««»»


Who Are the People With Multiple Sclerosis?Guest Article: Stem Cells Showing Great Promise in Remyelinization: A guest article by Daryl Clayton Kennedy.  ««»»


 

A Measure of Time - My Life With MSA Measure of Time - My Life With MS: This book by Lauren Singer is available directly from the author. This page on my site provides a tiny amount of publicity for this book. By the way, her dog is named Fred Huggins.   ««»»  

As for Tomorrow I Cannot Say: 33 Years with Multiple SclerosisAs for Tomorrow I Cannot Say: 33 Years with Multiple Sclerosis: I review this book by Diana Neutze.  ««»»  

Life on Cripple Creek - Essays on Living with Multiple SclerosisLife on Cripple Creek - essays on Living with Multiple Sclerosis: I review this book by Dean Kramer.  ««»»  

My Story: A Photographic Essay on Life with Multiple SclerosisMy Story: A Photographic essay on Life with Multiple Sclerosis: I review this book by Amelia Davis.  ««»»  

When the Road Turns - Inspirational Stories About People with MSWhen the Road Turns - Inspirational Stories About People with MS: I review this book by Margot Russell.  ««»»  


A Special Note If You Jumped Into My Site
Directly to This Page

This topic is just a part of my overall website. After you check out this topic, you might like to explore the rest of my site and get to know me better.  I recommend that you start with my "Home" Page, then go to the "Front Door", then to "Stuff About Me" and finally, just explore the site. The buttons on the left will take you there.


If You Would Like to Link to My Multiple Sclerosis Pages

Many webmasters only want people to link to the "primary" page of a website. I have a different view.

Because of the importance of Multiple Sclerosis to me I actually encourage other Multiple Sclerosis sites to link directly to my Multiple Sclerosis pages. Click here to find out my special requests for linking to my Multiple Sclerosis pages.


Awards

The following awards were awarded specifically for the
James S. Huggins' Refrigerator Door: Multiple Sclerosis Pages.

Outstanding Website Award
  1999 

sponsored by
Disability Network

Outstanding Website Award 1999
awarded 25.Oct.1999
by the Disability Network
  Winners List with my award listed and a link back to my site.

Editor's Choice Award from HealingWell.com

editor's Choice Award
awarded 26.Oct.1999
by HealingWell.com

Facing Challenge Award

Facing Challenge Award
awarded 30.Oct.1999
by Facing Challenge Award
  Winners List with my award listed and a link back to my site.

Helping Hands Award from Living With Multiple Sclerosis

Helping Hands Award
awarded 15.Nov.1999
by Living With Multiple Sclerosis
  Winners List with my award listed and a link back to my site.


Directory Links

This section of my site (James S. Huggins' Refrigerator Door: Multiple Sclerosis Pages), is listed in the following directories.

Good Health Directory

Good Health Directory
linked 20.Mar.2000

HealingWell.com

HealingWell.com
linked 26.Oct.1999
(see also editor's Choice Award above)

Member of Internet Health Library

Health-Library
linked 21.Aug.2000

A HealthLinks Select Site

HealthLinks
linked 02.Feb.2001

A MedExplorer Selected SIte

Medexplorer
linked 02.Feb.2001

 

This website is accredited by Health On the Net Foundation. Click to verify.

This site complies with the HONcode standard for trustworthy health information of the Health On the Net Foundation: you can verify that here.

Certified Medinex Health Site

This site was a Medinex Certified Health Site and subscribed to the Medinex Code of ethics.

[NB: The above links point to an archive previous page. hosted by the
Internet Archive Wayback Machine. The assets of Medinex were sold in a Chapter 11 bankruptcy sale in March 2003. The site is no longer functional.]

Disclaimer:  I am not a licensed or trained health care provider. I'm just a guy who cares (bunches) about Multiple Sclerosis and who spends (too much) time on the net. I provide the medical information on this website for educational and informational purposes only. It is not a substitute for a health care provider's care and consultation. Please consult your health care provider about any opinions or recommendations with respect to your own symptoms and conditions. Any treatment or nutritional product mentioned on this site is not intended or claimed to diagnose, treat, cure or prevent any disease. Please advise me of any errors or omissions you detect. I receive no funds from any medical products companies. And, I fully disclose all other product affiliations on the Disclaimers, Copyrights and Other Legal Stuff page on this site.

The extra text menu links (previously here) are being removed in the site redesign.
Browser and search engine improvements have eliminated the motivation/necessity for them.

This page created:
before
Wed, 10.May.2000

Last updated:
16:17, Sat, 10.May.2014

. . .

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 Explanation of the rewrite: New Page Layout.
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multiple sclerosis information, multiple sclerosis support groups, multiple sclerosis links, multiple sclerosis email lists, ms, neurological disease, myelin, multiple sclerosis research, ms research, nervous system, bee venom therapy, brain disorder, neurology, brain disease, multiple sclerosis foundation, multiple sclerosis society, ms society, neuroscience, qwerty . . . multiple sclerosis information, multiple sclerosis support groups, multiple sclerosis links, multiple sclerosis email lists, ms, neurological disease, myelin, multiple sclerosis research, ms research, nervous system, bee venom therapy, brain disorder, neurology, brain disease, multiple sclerosis foundation, multiple sclerosis society, ms society, neuroscience, qwerty